Juniper Publishers-Cancer Therapy Oncology International Journal

  Cancer Therapy & Oncology International Journal Abstract Introduction and Objective: This study was aimed to evaluate the QOL among BCS who receiving various treatment strategies in Teaching Hospital, Karapitiya (THK). Method: This cross sectional study was performed with conveniently selected 142 BCS (Mean age (SD) - 55 (10.29) years) at oncology unit of THK during July 2016 using WHOQOL-BREFF questionnaire. Results: Among the studied BCS, 32.4% were studied up to O/L and 61.3% were married. 76.8% were unemployed and 38.7% had monthly income between Rs 10,000-30,000. 51.4% were living with their husband and children and 93% were Buddhist. 34.5% had undergone to CT. Mean (SD) of physical (PD), psychological (PsD), social (SD) and environmental (ED) domains were 47.79 (11.20), 42.17 (15.19), 48.86 (15.68) and 51.83 (13.61) respectively. Age, marital status, level of education and monthly income and current treatments were significantly affect...

Cancer Therapy & Oncology - Juniper Publishers Abstract Medical Imaging is now being used extensively, in fact more than ever, for clinical trials for a new drug development. Medical imaging can be used through any of the available imaging modalities, including quantitative imaging with the help of CT, MRI or hybrid PET-CT. Much time and money can be saved in not proceeding with a clinical trial as imaging can predict fairly well and early about the efficacy of a compound for the disease process in its evaluation as a “Go-No Go” approach. FDA and other regulatory authorities also believe that medical imaging is a critical component in its Critical Path Opportunity List of 2006. It is significant to note that pharmaceutical companies and CROs employ imaging as its important tool to quantify matrix for its justification of introducing a new drug, but standardization in terms of patient positioning or the central reads have to be justified against in...

Juniper Publishers-Open Access Journal of Cancer Therapy and Oncology Chemoradiation with Capecitabine and Mitomycin-C for Stage I-III Anal Squamous Cell Carcinoma Authored by Hagen Kennecke Carcinoma of the anal canal is relatively uncommon, yet incidence is on the rise. The accepted current standard regimen for patients with stage I-III squamous cell carcinoma (SCC) of the anal canal is radiotherapy (50.4 Gy) with concurrent infusional 5-fluorouracil (5-FU) (825 mg/m2 per oral bi-daily) administered on radiation days during weeks one and five and mytomycin C (MMC) (12 mg/m2) administered on week one. This study describes the efficacy and safety of substituting oral capecitabine (Cap) for the infusional 5-FU and compares the planned versus delivered therapy, and describes treatment-related patient toxicities and early outcomes in a population-based setting. To Read More. . PHP  in  Cancer Therapy & Oncology International Journal  in Junip...