Juniper Publishers-Cancer Therapy Oncology International Journal

 Cancer Therapy & Oncology - Juniper Publishers Abstract Owing to the high prevalence of gynecological malignancies worldwide, it is of utmost importance to detect these malignancies early, thus reducing their morbidity and mortality rates. Imaging plays a significant role not only in detection but also, owing to the new functional techniques including perfusion MRI, in staging and directing treatment planes. In this article we review the different perfusion techniques used in endometrial, cervical and ovarian malignancies and the importance and potential benefits for their use. The importance of early and proper diagnosis of gynecologic malignancies lies in the fact that they contribute to a large number of female mortality and morbidity in the United States. Abbreviations: MRI: Magnetic Resonance Imaging; DCE-MRI: Dynamic Contrast Enhanced MRI; MVD: Microvessel Density; VEGF: Vascular Endothelial Growth Factor; IAUGC: Initial Area Under the Gadolinium Concentrat