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Showing posts with the label Cervical Cancer

Juniper Publishers - The Effect of Different Single Doses from X-Rays on Pediatrics Rhabdomyosarcoma Tumor Cells: In Vitro Survival Curve

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  Cancer Therapy & Oncology International Journal Abstract The purpose of the work was to study the effect of different single radiation doses of X-rays on the pediatrics Rhabdomyosarcoma (RMS) cells in vitro . In addition, to construct the survival curve for the RMS cells and determine some crucial radiobiological parameters used for calculations of tumor cell kill in radiotherapy treatment of pediatrics RMS tumors. An established in vitro cell culture model employing the RMS tumor cell lines was used for this study. Cells were exposed to single doses of 0, 4, 8, 12, 16, and 20 Gy from a 6 MV X-rays photon beam energy. The clonogenic cell survival assay method was used to quantify the RMS cell survival. The survival curve was fitted by the single-hit multi-target and linear-quadratic models. The mean lethal dose (D 0 =3.2 Gy), the extrapolated number (n=11) represents a measure of the width of the survival curve shoulder and corresponds to th...

Juniper publishers - The Psychological Aspects of the Treatments Involved in Cancer Quackery: Historical Review

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  Cancer Therapy & Oncology International Journal Abstract The place of quackery is important in the history of medicine. In this context, cancer quackery is in the forefront of it. Therefore, English literature and foreign translations are searched from 1635 to1886 in order to obtain some memorable perspectives of the psychological aspects of cancer quackery. Keywords: Quackery; Cancer; Treatment; Psychology; History Historical Perspectives Sir Macfarlane Burnet [1], who is far famed for his pioneer work on cancer surveillance, recommended clearly in his Brailsford Robertson Memorial Lecture that scientists should acquaint themselves with historical antecedents. Therefore, this paper documents such antecedents in respect of the drug treatment modalities used by cancer quacks. Quacks were presented in the 1725 History of Physic by Friend [2] concerning “how much ...

How Long Should Be The Radiation Oncology Treatment for Cervical Cancer? -Juniper Publishers

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Juniper Publishers-Open Access Journal of Cancer Therapy and Oncology How Long Should Be The Radiation Oncology Treatment for Cervical Cancer? Authored by Luis Moreno Sanchez Historically locally advanced cervical cancer was treated with teletherapy and a boost with brachytherapy. But in 1999 the treatment changed favorably, thus establishing the current management based on concurrent chemo-radiotherapy, thanks to the publication of some studies [1,2] that showed survival advantage of this disease with the addition of platinum-based chemotherapy and radiotherapy. To Read More.. PHP  in Cancer Therapy & Oncology International Journal  in Juniper Publishers

Can Dynamic Conformal arc be an Option in Epidermoid Cervical Cancer Treatment? - Juniper Publishers

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Juniper Publishers-Open Access Journal of Cancer Therapy and Oncology Can Dynamic Conformal arc be an Option in Epidermoid Cervical Cancer Treatment? Authored by  Jacksson S Historically locally advanced cancer of the cervix has been treated with radiotherapy and brachytherapy and it was not until 1999 that the use of concurrent chemotherapy was formalized due to excellent results in terms of rate of overall and disease-free survival. Box technique in radiotherapy is the most widely known providing excellent results, with some variations as oblique fields, but greatly increasing irradiation potentially healthy tissue, leading to the higher proportion of own side effects of each treatment. Therefore present a radiant treatment planning mode Dynamic Conformal Arc for cervical carcinoma.Treatment with dynamic conformal arc achieves better conformation of tumor and area to be treated, avoiding unnecessary doses to organs at risk (OAR), compared to conventional ...