Juniper Publishers-Cancer Therapy Oncology International Journal

  Cancer Therapy & Oncology- Juniper Publishers                                               Abstract Adenoid cystic carcinomas (ACC) represent 10% of all salivary tumors. It primarily affects the salivary glands particularly those located in the buccal cavity. Sinonasal location is rarely described [1]. We report a rare case of sinonasal adenoid cystic carcinoma (SACC), we discuss through a brief review of the literature its clinical, radiological, histopathological and therapeutic modalities and the prognostic factors of this tumor. Keywords:  Adenoid Cystic Carcinoma; Paranasal Sinus; Facial Pain Introduction ACC is a rare malignant neoplasm that accounts for 1-2% of all head and neck malignancies and approximately 10% of all salivary gland neoplasms [2]. It occurs predominantly among women, between the fifth and sixth decades of life [3]. Sinonasal Adenoc...

Cancer Therapy & Oncology - Juniper Publishers Abstract Medical Imaging is now being used extensively, in fact more than ever, for clinical trials for a new drug development. Medical imaging can be used through any of the available imaging modalities, including quantitative imaging with the help of CT, MRI or hybrid PET-CT. Much time and money can be saved in not proceeding with a clinical trial as imaging can predict fairly well and early about the efficacy of a compound for the disease process in its evaluation as a “Go-No Go” approach. FDA and other regulatory authorities also believe that medical imaging is a critical component in its Critical Path Opportunity List of 2006. It is significant to note that pharmaceutical companies and CROs employ imaging as its important tool to quantify matrix for its justification of introducing a new drug, but standardization in terms of patient positioning or the central reads have to be justified against in...

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