Thigh Muscle Bundle Volume by Magnetic Resonance Muscle Quantification (MRMQ) in Skeletal Muscle Wasting and Relevance of Supine Rest

Authored by Somya Aggarwal

MRI is beginning to be extensively used in clinical trials in the quantitative analysis of muscle volume in muscle wasting pathologies with the help of magnetic resonance muscle quantification (MRMQ). Muscle wasting occurs in various kinds of diseases, such as, muscular dystrophies, cachexia, sports injuries or ageing. This can results in progressive disability and eventually a possible deformity. Clinical trials are increasingly done to target an increase in the muscle volume by new drugs. The variability in measurement of the change in muscle volume needs standardization with accurately delineated measurement methods such as mid -thigh muscle bundle volume changes.

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