Juniper Publishers-Adult Wilms’ Tumor: Review of Literature

Juniper Publishers-Open Access Journal of Cancer


Adult Wilms’ Tumor: Review of Literature

Authored by Elsayed Mostafa Ali

The most common renal tumor in adults is renal cell carcinoma, wilms’ tumor is extremely rare in adults, representing only 0.5% of all renal neoplasms, 240 cases in adults have been reported [1]. The true incidence of adult wilms’ tumor is somewhat uncertain because of confusion in terminology and difficulties in clinical and pathological differential diagnosis [2]. Kilton et al. selected 35 real adult wilms’ tumor complying with 6 diagnostic criteria of 192 documented cases [3].  Patients with stage III, IV are reported to account for more than 50% of most adult series [4]. Until recent, exact data on prognosis and late effects are not available [5]. Prognosis for adult patients with unfavorable histology and stage IV disease (hematogenous metastasis) is poor despite aggressive multimodal therapy [6]. There is no standard therapy for treating patients with adult wilms’ tumor. Some authors suggest an aggressive treatment regardless of the stage, but a therapeutic procedure based on the NWTS with different treatment depending on tumor stage also has been recommended [7].

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